Chiyoda's Approach to Bio-Pharmaceutical Plants

Chiyoda has many experiences on constructing various facilities in the fields of mammalian cell culture and protein purification, including facilities for clinical trials which are used many SUBs(single-Use Bags) and for 10m³ manufacturing scale. In addition, Chiyoda, with its wide range of knowledge, can offer support in the design of various facilities such as tissue engineering, cell culture system in space.
Chiyoda can offer various O₂/CO₂ dynamic simulation analyses to fit each client’s production scale and optimal facility design (configuration/size) using batch simulators/CFD.

Genetically modified protein purification facility
Protein purification column system

O₂/CO₂ dynamic simulation in culture
Study of optimal O₂ feeding method and analysis in the flow of agitated tank

Feasibility study, and scale-up study
Culture plant that uses a single-use system